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Zinc oxide nanoparticles sterilization and disinfection mechanism

Roche and its subsidiary TIB Molbiol have developed a series of tests for the detection of the monkeypox virus, the Switzerland-based pharmaceutical company announced.  

The monkeypox virus is a close relative of the smallpox virus, belonging to orthpoxviridae in the poxviridae family.  

The modular virus detection tool, called LightMix, includes three orthpoxvirus detection kits with different functions, Roche said in a statement. The first kit detects orthpoxvirus; The second kit tests only for monkeypox virus (west and Central African branches); The third kit contains the main functions of the first two kits, showing specific information on the presence of the monkeypox virus (west and Central African branches) as well as the detection of orpoxvirus.

Thomas Schinek, a Roche executive, said the new test could detect monkeypox and help track its spread. Such diagnostic tools are critical for addressing and ultimately managing emerging public health challenges, as they advance responses such as tracking efforts and treatment strategies.  

The monkeypox virus was first identified in 1958 in a group of monkeys used for research when the animals developed a "pox-like" infection, hence the name. Since May, several non-endemic countries have reported human cases of the monkeypox virus, including the United Kingdom, the United States, Portugal, Spain, and Italy.

Affected by the ever-changing international situation, the supply and prices of international bulk zinc oxide are still very uncertain.

Nano zinc oxide can be used in surface coating products and used in space vehicles, and there has been research on the application of nano-materials in industry, such as ceramic and rubber industry. Nowadays, the research of nano-drug delivery system and nano-drugs has been paid more and more attention by researchers, and nano-materials have been gradually applied to the medical field.

Nano zinc oxide is a new type of high-performance fine inorganic material facing the 21 century. The particle size of n is about 1~100nm. Because the particle size is too fine, the electronic structure and crystal structure of nano ZnO have changed, resulting in properties that macroscopic objects do not have, such as quantum size effect, surface effect, macroscopic tunneling effect and so on.
 

Zinc oxide nanoparticles sterilization and disinfection mechanism
1. Nano zinc oxide can continuously release zinc ions in aqueous medium, zinc ions will enter the cell membrane, destroy the cell membrane, and destroy the spatial structure of bacteria and proteins when they react with some protein groups in the cell. causes the protease in the cell to inactivate and kill the bacteria. After destruction, zinc ions will dissociate from the bacteria and repeat the sterilization process.
 
2. Nanometer zinc oxide can interact with the cell wall on the surface of bacteria, destroy the cell wall of bacteria, and cause the contents to be released to kill bacteria.
 
3. Under the irradiation of ultraviolet light, nano ZnO will produce hole electron pairs, electrons and holes migrate from the conduction band and valence band to the surface of zinc oxide particles, respectively, and the water or hydroxyl groups adsorbed on the surface are converted into hydroxyl radicals, and the adsorbed oxygen is transformed into reactive oxygen species. Hydrogen oxygen free radicals and reactive oxygen species have strong chemical activity and can react with most organic compounds to kill most bacteria and viruses. Because the particle size of nanometer zinc oxide is too small, the time of electrons and holes from the conduction band and valence band to the crystal surface is greatly reduced, and the probability of hole and electron recombination is also reduced, so the antibacterial property of zinc oxide with nanometer particle size is better.
 
The related experiments show that the germicidal rate increases obviously with the increase of the concentration of nanometer zinc oxide suspension, indicating that the germicidal efficacy is better, and the germicidal efficacy of Staphylococcus aureus is obviously better than that of Escherichia coli as the treatment time. The above experimental results show that nanometer zinc oxide suspension has germicidal efficacy.
 

Zinc Oxide Nanoparticles Uses
1. The manufacture of surgical clothes
Nanometer zinc oxide can absorb and scatter ultraviolet radiation, so it has the function of shielding ultraviolet radiation. Because nanometer zinc oxide is a direct band gap semiconductor, when receiving ultraviolet radiation, the electrons in the valence band can absorb the energy of ultraviolet radiation and transition to the conduction band. After the transition, hole electron pairs will be produced, and ultraviolet radiation will also be absorbed. In addition, when the long-term wavelength of UV light is larger than the particle size of nano-ZnO, the nanoparticles can scatter medium-and long-wave UV in all directions, thus reducing the intensity of UV in the irradiation direction. The particle size range of nanometer zinc oxide is generally 1-100 nm, and the ultraviolet wavelength range is 100-400 nm, so nano-zinc oxide has better shielding effect on long-wave ultraviolet (wavelength 320-400 nm) and medium-wave ultraviolet (wavelength 280-320 nm). Compared with organic ultraviolet absorbers, nanometer zinc oxide is safe, stable and reliable, and can be used as ultraviolet shielding agent and fiber materials. The nanometer zinc oxide VK-J30 produced by our company has a particle size of 30 nm and has good dispersibility in the medium used.
 
2. Used in dentistry
The lack of strength of the composite resin used in early dental treatment often leads to treatment failure, resulting in a mixed composite resin with better performance. Because nano-ZnO crystal needs complete structure, almost no internal defects, high strength and high modulus, and its unique three-dimensional tetragonal shape can change the mechanical properties of the material isotropic, so adding it to the composite resin system can significantly improve the mechanical properties of the composite resin. At the same time, nanometer zinc oxide can be applied to dental resin to replace traditional porcelain teeth because of its antibacterial properties.
 
Nano Zinc Oxide Price
The price is influenced by many factors including the supply and demand in the market, industry trends, economic activity, market sentiment, and unexpected events.
If you are looking for the latest zinc oxide nanoparticles price, you can send us your inquiry for a quote. (sales3@nanotrun.com)
 
Nano Zinc Oxide Supplier
Luoyang Tongrun Nano Technology Co. Ltd. (TRUNNANO) is a trusted zinc oxide manufacturer and zinc oxide supplier with over 12-year-experience. We ship our goods all over the world.
 
If you are looking for high-quality zinc oxide powder, please feel free to contact us and send an inquiry. (sales3@nanotrun.com)

 

Bola Carbon, the global black carbon giant, recently announced that it is raising the price of all black carbon zinc oxide.

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