Is titanium dioxide harmful to the body?

According to the latest quarterly analysis of the natural gas market released by the International Energy Agency, global natural gas consumption will decline slightly this year and increase slowly in the following years because of soaring prices and the possibility of further reductions in Russian natural gas supplies. Global natural gas use this year is expected to be 0.5% lower than the 2021 level, and global natural gas demand is expected to increase by only 140 billion cubic meters over 2021 by 2025, the report said. The annual growth in 2021 will reach 175 billion cubic meters.

At the same time, the IEA's forecast for natural gas demand growth by 2024 was 60 per cent lower than its previous forecast, mainly due to "a weak economy and a smaller energy shift from coal or oil to natural gas", the report said.

It is worth noting that the South Korean Ministry of Industry, Trade and Resources announced on the same day that it plans to increase the proportion of nuclear power in South Korea's national energy structure to more than 30% by 2030. The proportion is 27.4% in 2021. The department also announced the resumption of the construction of two nuclear reactors. According to reports, after taking office, South Korean President Yoon Sik-Yue rejected the previous government's plan to phase out nuclear power and promised to increase investment in the nuclear power industry, so as to regain South Korea's status as a major exporter of safe nuclear reactors.

In addition, the supply and prices of many international bulk titanium dioxide are still very uncertain.

US consumers recently filed a lawsuit against Mars in a California court, claiming that the content of titanium dioxide in Skittles was too high.

According to an indictment filed by US consumers, titanium dioxide can cause changes in DNA in the human body, damage organs such as the brain, and damage the liver and kidneys. The European Food Safety Agency (EFSA) issued a report in May 2021 that, given all available scientific research and data, titanium dioxide is no longer safe as a food additive.

What is titanium dioxide?

Titanium dioxide, chemical formula TiO2, as an additive code is 171.

Because of its non-toxic, best opacity, best whiteness and brightness, it has been widely used in many fields, such as paint, plastic, rubber, paper, cosmetics, food, medicine and so on.

Titanium dioxide used in pharmaceutical industry

In the pharmaceutical industry, titanium dioxide is often used in pharmaceutical preparations, as a coating agent, colorant and ultraviolet absorbent, for the preparation of coated tablets, pills, granules, capsules and topical preparations.

According to the European Union Trade Association, about 91000 drugs for human use and 800 kinds of veterinary drugs contain titanium dioxide. According to an article published by the European Drug Administration in September 2021 to assess the impact of titanium dioxide on the pharmaceutical industry: it is difficult for the pharmaceutical industry to get rid of titanium dioxide, and this excipient is frequently used in oral solid and semi-solid dosage forms as opaque agents and colorants. such as tablets, capsules, suspensions and so on. It also exists in many essential drugs for human beings, including antibiotics, antidiabetic drugs and so on.

Who is to blame?

It is said that the safety problem of titanium dioxide is not titanium dioxide itself, but a certain proportion of nanometer titanium dioxide. Nano-sized particles may be harmful to human health.

Can titanium dioxide be replaced?

It is not easy to find a replacement for titanium dioxide.

The European Drug Administration has reported that so far, no single substance has been found to provide a combination of properties unique to TiO2 (such as opacity, enhanced contrast, inertia, UV protection and the resulting product smoothness).

Possible alternatives include calcium carbonate, talc, and starch. However, these alternatives have disadvantages (for example, inability to obtain thin enough film, supply chain problems, and the risk of related element impurities).

According to the European Drug Administration, if titanium dioxide is not allowed to add to medicines, it will almost cause a large shortage of drugs and lead to the suspension / withdrawal of these drugs from the EU / European Economic area market. The European Drug Administration's quality working Group (QWP) said there was currently no mechanism for regulators to prioritize products to be reformulated and that the transition period for replacing titanium dioxide would take a decade or more. "each affected pharmaceutical product will require a separate review and evaluation, which will require investigation of alternatives, product reformulation, and collection of new data related to manufacturing, dissolution and stability." The European Drug Administration wrote.

Some enterprises have begun to study alternatives to titanium dioxide. for example, the food company ADM has launched a series of white colorant solutions series Pearl Edge, which aims to replace food-grade titanium dioxide, and Caracom, a manufacturer of thin-film coating systems in the pharmaceutical industry, has launched the Newterfield series of full-formula thin-film coating products designed for nutrition, which clearly states that it does not contain titanium dioxide.

Titanium dioxide TiO2 powder Price

The price is influenced by many factors including the supply and demand in the market, industry trends, economic activity, market sentiment, and unexpected events.

If you are looking for the latest TiO2 powder price, you can send us your inquiry for a quote. (sales1@rboschco.com)

Titanium dioxide TiO2 powder Supplier

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Albemarle, the world's largest lithium producer, said it would have to close its plant in Langelsheim, Germany if the EU designated lithium as a hazardous material. The European Commission is currently evaluating a proposal by the European Chemicals Agency (EHCA) to classify lithium carbonate, lithium chloride, and lithium hydroxide as hazardous to human health.

As a result, Albemarle will no longer be able to import lithium chloride, its main raw material, putting its entire plant in Langelsheim at risk of closure, Albemarle chief financial Officer Scott Tozier said. According to Tozier, the plant has annual sales of about $500 million and a forced closure would have a significant impact on Albemarle's operations.  

Industry sources said that listing lithium as a hazardous substance would place an additional burden on the titanium dioxide, please feel free to contact us and send an inquiry.

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